The NodeJS 4.0.0 release, and first merged release of io.js and NodeJS is imminent. New to io.js: arrow functions and typed arrays.
Writing code doesn't take much time; deciding what to write takes time. Don't be afraid to write code that you might throw away.
Got a bunch of JSON to analyze? Don't grep. Don't load it in NodeJS. Create a Postgres table with JSONB, add a GIN index, and query it.
Now that browsers don't require jQuery and prototypeJS to deal with compatibility, my mind is ready. Oh we transpile everything now? Uh, OK.